Synthesized peptide derived from human protein . at AA range: 170-250
Storage:
Rabbit
Storage:
-20°C/1 year
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1 mg/ml
Observed Band:
44kD
GeneID（Human）:
59338
Human Swiss-Prot No:
Q9HB21
Cellular localization:
Cytoplasm . Cell membrane ; Peripheral membrane protein. Nucleus . Locates to the plasma membrane after treatments that stimulate the production of PtdIns3,4P2. .
Background:
This gene encodes a pleckstrin homology domain-containing adapter protein. The encoded protein is localized to the plasma membrane where it specifically binds phosphatidylinositol 3,4-bisphosphate. This protein may be involved in the formation of signaling complexes in the plasma membrane. Polymorphisms in this gene are associated with age-related macular degeneration. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5.[provided by RefSeq, Sep 2010],
