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ELK Biotechnology
SKU:ES11352
SMC1B Rabbit Polyclonal Antibody
SMC1B Rabbit Polyclonal Antibody
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$248.00 USD
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SMC1B Rabbit Polyclonal Antibody
Overview
| Product name: | SMC1B rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 110-190 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 135kD |
| GeneID（Human）: | 27127 |
| Human Swiss-Prot No: | Q8NDV3 |
| Cellular localization: | Nucleus . Chromosome . Chromosome, centromere . Associates with chromatin. In prophase I stage of meiosis, localizes along the AE of synaptonemal complexes. In late-pachytene-diplotene, the bulk of protein dissociates from the chromosome arms probably because of phosphorylation by PLK, except at centromeres, where cohesin complexes remain. Remains chromatin associated at the centromeres up to metaphase II. At anaphase II, dissociates from centromeres, allowing chromosomes segregation (By similarity). . |
| Background: | structural maintenance of chromosomes 1B(SMC1B) Homo sapiens SMC1L2 belongs to a family of proteins required for chromatid cohesion and DNA recombination during meiosis and mitosis (3:Revenkova et al., 2001 [PubMed 11564881]).[supplied by OMIM, Mar 2008], |
| Species Reactivity: | Human;Rat;Mouse; |
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