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ELK Biotechnology
SKU:ES11348
BACE2 Rabbit Polyclonal Antibody
BACE2 Rabbit Polyclonal Antibody
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$248.00 USD
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BACE2 Rabbit Polyclonal Antibody
Overview
| Product name: | BACE2 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 210-290 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 56kD |
| GeneID(Human): | 25825 |
| Human Swiss-Prot No: | Q9Y5Z0 |
| Cellular localization: | Cell membrane ; Single-pass type I membrane protein . Golgi apparatus . Endoplasmic reticulum. Endosome. |
| Background: | This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013], |
| Species Reactivity: | Human;Rat;Mouse |
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