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ELK Biotechnology
SKU:ES11321
PTN14 Rabbit Polyclonal Antibody
PTN14 Rabbit Polyclonal Antibody
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$248.00 USD
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PTN14 Rabbit Polyclonal Antibody
Overview
| Product name: | PTN14 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from part region of human protein |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 130kD |
| GeneID（Human）: | 5784 |
| Human Swiss-Prot No: | Q15678 |
| Cellular localization: | Cytoplasm. Cytoplasm, cytoskeleton . Nucleus. Translocation into the nucleus is associated with induction of cell proliferation. Partially colocalized with actin filaments at the plasma membrane. |
| Background: | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal noncatalytic domain similar to that of band 4.1 superfamily cytoskeleton-associated proteins, which suggested the membrane or cytoskeleton localization of this protein. It appears to regulate lymphatic development in mammals, and a loss of function mutation has been found in a kindred with a lymphedema-choanal atresia. [provided by RefSeq, Sep 2010], |
| Species Reactivity: | Human;Mouse |
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