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ELK Biotechnology
SKU:ES11303
DSC2 Rabbit Polyclonal Antibody
DSC2 Rabbit Polyclonal Antibody
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$248.00 USD
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DSC2 Rabbit Polyclonal Antibody
Overview
| Product name: | DSC2 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 150-230 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 99kD |
| GeneID（Human）: | 1824 |
| Human Swiss-Prot No: | Q02487 |
| Cellular localization: | Cell membrane ; Single-pass type I membrane protein . Cell junction, desmosome . |
| Background: | This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015], |
| Species Reactivity: | Human;Mouse |
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