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ELK Biotechnology
SKU:ES11302
DISP1 Rabbit Polyclonal Antibody
DISP1 Rabbit Polyclonal Antibody
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$248.00 USD
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DISP1 Rabbit Polyclonal Antibody
Overview
| Product name: | DISP1 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 270-350 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 167kD |
| GeneID(Human): | 84976 |
| Human Swiss-Prot No: | Q96F81 |
| Cellular localization: | Membrane ; Multi-pass membrane protein . |
| Background: | The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure. A novel segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling. This gene is one of two human homologs of Drosophila dispatched and, based on sequence identity to its mouse counterpart, the encoded protein may play an essential role in Hh patterning activities in the early embryo. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Mouse |
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