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ELK Biotechnology
SKU:ES11281
FLRT2 Rabbit Polyclonal Antibody
FLRT2 Rabbit Polyclonal Antibody
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$248.00 USD
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FLRT2 Rabbit Polyclonal Antibody
Overview
| Product name: | FLRT2 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 170-250 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 72kD |
| GeneID（Human）: | 23768 |
| Human Swiss-Prot No: | O43155 |
| Cellular localization: | Cell membrane ; Single-pass membrane protein . Endoplasmic reticulum membrane . Cell junction, focal adhesion . Secreted, extracellular space, extracellular matrix . Microsome membrane . Secreted . Cell junction, synapse, synaptosome . Proteolytic cleavage gives rise to a shedded ectodomain. . |
| Background: | fibronectin leucine rich transmembrane protein 2(FLRT2) Homo sapiens This gene encodes a member of the fibronectin leucine rich transmembrane (FLRT) family of cell adhesion molecules, which regulate early embryonic vascular and neural development. The encoded type I transmembrane protein has an extracellular region consisting of an N-terminal leucine-rich repeat domain and a type 3 fibronectin domain, followed by a transmembrane domain and a short C-terminal cytoplasmic tail domain. It functions as both a homophilic cell adhesion molecule and a heterophilic chemorepellent through its interaction with members of the uncoordinated-5 receptor family. Proteolytic removal of the extracellular region controls the migration of neurons in the developing cortex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016], |
| Species Reactivity: | Human;Rat;Mouse; |
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