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ELK Biotechnology
SKU:ES11280
TPP1 Rabbit Polyclonal Antibody
TPP1 Rabbit Polyclonal Antibody
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$248.00 USD
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TPP1 Rabbit Polyclonal Antibody
Overview
| Product name: | TPP1 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 10-90 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 61kD |
| GeneID（Human）: | 1200 |
| Human Swiss-Prot No: | O14773 |
| Cellular localization: | Lysosome . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV. . |
| Background: | This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Rat;Mouse |
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