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ELK Biotechnology

SKU:ES11254

CSPG4 Rabbit Polyclonal Antibody

CSPG4 Rabbit Polyclonal Antibody

Regular price $248.00 USD
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CSPG4 Rabbit Polyclonal Antibody

Overview

Product name: CSPG4 rabbit pAb
Applications: IHC;IF
Recommended Dilutions: IHC-p 1:50-300
Immunogen: Synthesized peptide derived from human protein . at AA range: 1910-1990
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 255kD
GeneID(Human): 1464
Human Swiss-Prot No: Q6UVK1
Cellular localization: Cell membrane ; Single-pass type I membrane protein ; Extracellular side . Apical cell membrane ; Single-pass type I membrane protein ; Extracellular side . Cell projection, lamellipodium membrane ; Single-pass type I membrane protein ; Extracellular side . Cell surface . Localized at the apical plasma membrane it relocalizes to the lamellipodia of astrocytoma upon phosphorylation by PRKCA. Localizes to the retraction fibers. Localizes to the plasma membrane of oligodendrocytes (By similarity). .
Background: A human melanoma-associated chondroitin sulfate proteoglycan plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. CSPG4 represents an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Rat;Mouse
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