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ELK Biotechnology
SKU:ES11242
MMP24 Rabbit Polyclonal Antibody
MMP24 Rabbit Polyclonal Antibody
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$248.00 USD
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MMP24 Rabbit Polyclonal Antibody
Overview
| Product name: | MMP24 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 520-600 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 70kD |
| GeneID（Human）: | 10893 |
| Human Swiss-Prot No: | Q9Y5R2 |
| Cellular localization: | [Matrix metalloproteinase-24]: Cell membrane ; Single-pass type I membrane protein . Golgi apparatus, trans-Golgi network membrane ; Single-pass type I membrane protein . Recycled back to the plasma membrane through the trans-Golgi network via interaction with APBA3. .; [Processed matrix metalloproteinase-24]: Secreted, extracellular space, extracellular matrix . Also shed from cell surface as soluble proteinase, by a proteolytic cleavage. . |
| Background: | This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. Unlike most MMPs, which are secreted, this protease is a member of the membrane-type MMP (MT-MMP) subfamily, contains a transmembrane domain and is expressed at the cell surface. Substrates of this protease include the proteins cadherin 2 and matrix metallopeptidase 2 (also known as 72 kDa type IV collagenase). [provided by RefSeq, Feb 2016], |
| Species Reactivity: | Human;Rat;Mouse |
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