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ELK Biotechnology
SKU:ES11239
TNR21 Rabbit Polyclonal Antibody
TNR21 Rabbit Polyclonal Antibody
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$248.00 USD
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TNR21 Rabbit Polyclonal Antibody
Overview
| Product name: | TNR21 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 430-510 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 72kD |
| GeneID（Human）: | 27242 |
| Human Swiss-Prot No: | O75509 |
| Cellular localization: | Cell membrane ; Single-pass type I membrane protein . |
| Background: | This gene encodes a member of the tumor necrosis factor receptor superfamily. The encoded protein activates nuclear factor kappa-B and mitogen-activated protein kinase 8 (also called c-Jun N-terminal kinase 1), and induces cell apoptosis. Through its death domain, the encoded receptor interacts with tumor necrosis factor receptor type 1-associated death domain (TRADD) protein, which is known to mediate signal transduction of tumor necrosis factor receptors. Knockout studies in mice suggest that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation. [provided by RefSeq, Jul 2013], |
| Species Reactivity: | Human;Mouse |
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