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ELK Biotechnology
SKU:ES11190
GFRA2 Rabbit Polyclonal Antibody
GFRA2 Rabbit Polyclonal Antibody
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$248.00 USD
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GFRA2 Rabbit Polyclonal Antibody
Overview
| Product name: | GFRA2 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 320-400 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 51kD |
| GeneID（Human）: | 2675 |
| Human Swiss-Prot No: | O00451 |
| Cellular localization: | Cell membrane ; Lipid-anchor, GPI-anchor . |
| Background: | Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009], |
| Species Reactivity: | Human;Mouse |
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