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ELK Biotechnology
SKU:ES11179
RARG Rabbit Polyclonal Antibody
RARG Rabbit Polyclonal Antibody
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$248.00 USD
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RARG Rabbit Polyclonal Antibody
Overview
| Product name: | RARG rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 360-440 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 49kD |
| GeneID（Human）: | 5916 |
| Human Swiss-Prot No: | P13631 |
| Cellular localization: | Nucleus . Cytoplasm . |
| Background: | This gene encodes a retinoic acid receptor that belongs to the nuclear hormone receptor family. Retinoic acid receptors (RARs) act as ligand-dependent transcriptional regulators. When bound to ligands, RARs activate transcription by binding as heterodimers to the retinoic acid response elements (RARE) found in the promoter regions of the target genes. In their unbound form, RARs repress transcription of their target genes. RARs are involved in various biological processes, including limb bud development, skeletal growth, and matrix homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011], |
| Species Reactivity: | Human;Mouse |
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