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ELK Biotechnology

SKU:ES11114

ECE2 Rabbit Polyclonal Antibody

ECE2 Rabbit Polyclonal Antibody

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ECE2 Rabbit Polyclonal Antibody

Overview

Product name: ECE2 rabbit pAb
Applications: WB;ELISA
Recommended Dilutions: WB 1:500-2000 ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from part region of human protein
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 97kD
GeneID(Human): 9718
Human Swiss-Prot No: O60344
Cellular localization: Golgi membrane,integral component of membrane,cytoplasmic vesicle membrane,
Background: This gene encodes a member of the M13 family, which includes type 2 integral membrane metallopeptidases. The encoded enzyme is a membrane-bound zinc-dependent metalloprotease. The enzyme catalyzes the cleavage of big endothelin to produce the vasoconstrictor endothelin-1, and plays a role in the processing of several neuroendocrine peptides. It may also have methyltransferase activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013],
Species Reactivity: Human;Mouse

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