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ELK Biotechnology
SKU:ES11067
ATS5 Rabbit Polyclonal Antibody
ATS5 Rabbit Polyclonal Antibody
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$248.00 USD
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ATS5 Rabbit Polyclonal Antibody
Overview
| Product name: | ATS5 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from part region of human protein |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 102kD |
| GeneID（Human）: | 11096 |
| Human Swiss-Prot No: | Q9UNA0 |
| Cellular localization: | Secreted, extracellular space, extracellular matrix . |
| Background: | This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs and functions as an aggrecanase that cleaves aggrecan, a major proteoglycan of cartilage, and may mediate cartilage destruction in osteoarthritis. [provided by RefSeq, Feb 2016], |
| Species Reactivity: | Human;Mouse |
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