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ELK Biotechnology
SKU:ES11053
N2DL1 Rabbit Polyclonal Antibody
N2DL1 Rabbit Polyclonal Antibody
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$248.00 USD
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N2DL1 Rabbit Polyclonal Antibody
Overview
| Product name: | N2DL1 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from part region of human protein |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 26kD |
| GeneID（Human）: | 80329 |
| Human Swiss-Prot No: | Q9BZM6 |
| Cellular localization: | Cell membrane ; Lipid-anchor, GPI-anchor . Endoplasmic reticulum . In CMV-infected fibroblasts, detected in the endoplasmic reticulum/cis-Golgi. . |
| Background: | The protein encoded by this gene is a ligand of natural killer group 2, member D (NKG2D), an immune system-activating receptor on NK cells and T-cells. Binding of the encoded ligand to NKG2D leads to activation of several signal transduction pathways, including those of JAK2, STAT5, ERK and PI3K kinase/Akt. Also, in cytomegalovirus-infected cells, this ligand binds the UL16 glycoprotein and is prevented from activating the immune system. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015], |
| Species Reactivity: | Human;Rat;Mouse; |
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