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ELK Biotechnology
SKU:ES10939
PTPRG Rabbit Polyclonal Antibody
PTPRG Rabbit Polyclonal Antibody
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$248.00 USD
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PTPRG Rabbit Polyclonal Antibody
Overview
| Product name: | PTPRG rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from part region of human protein |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 158kD |
| GeneID(Human): | 5793 |
| Human Swiss-Prot No: | P23470 |
| Cellular localization: | Membrane ; Single-pass type I membrane protein . |
| Background: | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. This gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Mouse |
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