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ELK Biotechnology
SKU:ES10920
MYH11 Rabbit Polyclonal Antibody
MYH11 Rabbit Polyclonal Antibody
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$248.00 USD
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MYH11 Rabbit Polyclonal Antibody
Overview
| Product name: | MYH11 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from part region of human protein |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 216kD |
| GeneID（Human）: | 4629 |
| Human Swiss-Prot No: | P35749 |
| Cellular localization: | Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Thick filaments of the myofibrils. |
| Background: | The protein encoded by this gene is a smooth muscle myosin belonging to the myosin heavy chain family. The gene product is a subunit of a hexameric protein that consists of two heavy chain subunits and two pairs of non-identical light chain subunits. It functions as a major contractile protein, converting chemical energy into mechanical energy through the hydrolysis of ATP. The gene encoding a human ortholog of rat NUDE1 is transcribed from the reverse strand of this gene, and its 3' end overlaps with that of the latter. The pericentric inversion of chromosome 16 [inv(16)(p13q22)] produces a chimeric transcript that encodes a protein consisting of the first 165 residues from the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain. This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype. Alter |
| Species Reactivity: | Human;Rat;Mouse; |
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