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ELK Biotechnology
SKU:ES10827
SIK2 Rabbit Polyclonal Antibody
SIK2 Rabbit Polyclonal Antibody
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$248.00 USD
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SIK2 Rabbit Polyclonal Antibody
Overview
| Product name: | SIK2 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from part region of human protein |
| Storage: | -20°C/1 year |
| Storage: | Rabbit |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 101kD |
| GeneID（Human）: | 23235 |
| Human Swiss-Prot No: | Q9H0K1 |
| Cellular localization: | Cytoplasm . Endoplasmic reticulum membrane . |
| Background: | catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by phosphorylation on Thr-175 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39.,function:Phosphorylates 'Ser-794' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. Inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. AMPK subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 UBA domain.,subunit:Interacts with and phosphorylates TORC2/CRTC2., |
| Species Reactivity: | Human;Mouse |
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