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ELK Biotechnology
SKU:ES10822
KPCD3 Rabbit Polyclonal Antibody
KPCD3 Rabbit Polyclonal Antibody
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$248.00 USD
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KPCD3 Rabbit Polyclonal Antibody
Overview
| Product name: | KPCD3 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from part region of human protein |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 97kD |
| GeneID（Human）: | 23683 |
| Human Swiss-Prot No: | O94806 |
| Cellular localization: | Cytoplasm . Membrane . Translocation to the cell membrane is required for kinase activation. |
| Background: | This gene belongs to the multigene protein kinase D family of serine/threonine kinases, which bind diacylglycerol and phorbol esters. Members of this family are characterized by an N-terminal regulatory domain comprised of a tandem repeat of cysteine-rich zinc-finger motifs and a pleckstrin domain. The C-terminal region contains the catalytic domain and is distantly related to calcium-regulated kinases. Catalytic activity of this enzyme promotes its nuclear localization. This protein has been implicated in a variety of functions including negative regulation of human airway epithelial barrier formation, growth regulation of breast and prostate cancer cells, and vesicle trafficking. [provided by RefSeq, Jan 2015], |
| Species Reactivity: | Human;Mouse |
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