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ELK Biotechnology
SKU:ES10819
NUAK2 Rabbit Polyclonal Antibody
NUAK2 Rabbit Polyclonal Antibody
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$248.00 USD
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NUAK2 Rabbit Polyclonal Antibody
Overview
| Product name: | NUAK2 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from part region of human protein |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 69kD |
| GeneID（Human）: | 81788 |
| Human Swiss-Prot No: | Q9H093 |
| Cellular localization: | nucleus,cytoplasm,nuclear speck, |
| Background: | catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by phosphorylation on Thr-208 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39.,function:Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells.,PTM:Autophosphorylated in vitro.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.,similarity:Contains 1 protein kinase domain., |
| Species Reactivity: | Human;Rat;Mouse; |
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