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ELK Biotechnology
SKU:ES10805
ANPRB Rabbit Polyclonal Antibody
ANPRB Rabbit Polyclonal Antibody
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$248.00 USD
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ANPRB Rabbit Polyclonal Antibody
Overview
| Product name: | ANPRB rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from part region of human protein |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 115kD |
| GeneID(Human): | 4882 |
| Human Swiss-Prot No: | P20594 |
| Cellular localization: | Cell membrane ; Single-pass type I membrane protein . |
| Background: | This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Mouse;Rat |
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