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ELK Biotechnology
SKU:ES10755
CR3L3 Rabbit Polyclonal Antibody
CR3L3 Rabbit Polyclonal Antibody
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$248.00 USD
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CR3L3 Rabbit Polyclonal Antibody
Overview
| Product name: | CR3L3 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from part region of human protein AA range: 1-100 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 50kD |
| GeneID（Human）: | 84699 |
| Human Swiss-Prot No: | Q68CJ9 |
| Cellular localization: | Endoplasmic reticulum membrane ; Single-pass type II membrane protein .; [Processed cyclic AMP-responsive element-binding protein 3-like protein 3]: Nucleus . Under ER stress the cleaved N-terminal cytoplasmic domain translocates into the nucleus. |
| Background: | This gene encodes a member of the basic-leucine zipper family and the AMP-dependent transcription factor family. The encoded protein is localized to the endoplasmic reticulum and acts as a transcription factor activated by cyclic AMP stimulation. The encoded protein binds the cyclic AMP response element (CRE) and the box-B element and has been linked to acute inflammatory response, hepatocellular carcinoma, triglyceride metabolism, and hepcidin expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012], |
| Species Reactivity: | Human;Mouse;Rat |
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