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ELK Biotechnology
SKU:ES10749
MCM9 Rabbit Polyclonal Antibody
MCM9 Rabbit Polyclonal Antibody
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$248.00 USD
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MCM9 Rabbit Polyclonal Antibody
Overview
| Product name: | MCM9 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from part region of human protein |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 125kD |
| GeneID（Human）: | 254394 |
| Human Swiss-Prot No: | Q9NXL9 |
| Cellular localization: | Nucleus . Chromosome . Colocalizes to nuclear foci with RPA1 following DNA damage (PubMed:23401855). Localizes to double-stranded DNA breaks (PubMed:23401855). Recruited to chromatin by MSH2 (PubMed:26300262). . |
| Background: | The protein encoded by this gene is a member of the mini-chromosome maintenance (MCM) protein family that are essential for the initiation of eukaryotic genome replication. Binding of this protein to chromatin has been shown to be a pre-requisite for recruiting the MCM2-7 helicase to DNA replication origins. This protein also binds, and is a positive regulator of, the chromatin licensing and DNA replication factor 1, CDT1. [provided by RefSeq, Nov 2010], |
| Species Reactivity: | Human;Rat;Mouse; |
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