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ELK Biotechnology

SKU:ES10743

APC4 Rabbit Polyclonal Antibody

APC4 Rabbit Polyclonal Antibody

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APC4 Rabbit Polyclonal Antibody

Overview

Product name: APC4 rabbit pAb
Applications: WB;ELISA
Recommended Dilutions: WB 1:500-2000 ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from part region of human protein
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 88kD
GeneID(Human): 29945
Human Swiss-Prot No: Q9UJX5
Cellular localization: Nucleus .
Background: A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The exact function of this gene product is not known. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013],
Species Reactivity: Human;Mouse
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