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ELK Biotechnology
SKU:ES10635
ROAA Rabbit Polyclonal Antibody
ROAA Rabbit Polyclonal Antibody
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$248.00 USD
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ROAA Rabbit Polyclonal Antibody
Overview
| Product name: | ROAA rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from part region of human protein |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 36kD |
| GeneID(Human): | 3182 |
| Human Swiss-Prot No: | Q99729 |
| Cellular localization: | Nucleus . Cytoplasm . Localized in cytoplasmic mRNP granules containing untranslated mRNAs. |
| Background: | This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are produced by RNA polymerase II and are components of the heterogeneous nuclear RNA (hnRNA) complexes. They are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene, which binds to one of the components of the multiprotein editosome complex, has two repeats of quasi-RRM (RNA recognition motif) domains that bind to RNAs. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Mouse |
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