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ELK Biotechnology
SKU:ES10609
XRN1 Rabbit Polyclonal Antibody
XRN1 Rabbit Polyclonal Antibody
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$248.00 USD
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XRN1 Rabbit Polyclonal Antibody
Overview
| Product name: | XRN1 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from part region of human protein |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 187kD |
| GeneID（Human）: | 54464 |
| Human Swiss-Prot No: | Q8IZH2 |
| Cellular localization: | Cytoplasm . Discrete foci at the inner surface of the cell membrane. |
| Background: | This gene encodes a member of the 5'-3' exonuclease family. The encoded protein may be involved in replication-dependent histone mRNA degradation, and interacts directly with the enhancer of mRNA-decapping protein 4. In addition to mRNA metabolism, a similar protein in yeast has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly. Mutations in this gene are associated with osteosarcoma, suggesting that the encoded protein may also play a role in bone formation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013], |
| Species Reactivity: | Human;Mouse |
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