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ELK Biotechnology
SKU:ES10588
KDM4D Rabbit Polyclonal Antibody
KDM4D Rabbit Polyclonal Antibody
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$248.00 USD
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KDM4D Rabbit Polyclonal Antibody
Overview
| Product name: | KDM4D rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 400-480 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 57kD |
| GeneID（Human）: | 55693 |
| Human Swiss-Prot No: | Q6B0I6 |
| Cellular localization: | Nucleus . |
| Background: | caution:It is uncertain whether Met-1 or Met-4 is the initiator.,cofactor:Binds 1 Fe(2+) ion per subunit.,function:Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys-9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.,similarity:Belongs to the JHDM3 histone demethylase family.,similarity:Contains 1 JmjC domain.,similarity:Contains 1 JmjN domain., |
| Species Reactivity: | Human;Rat;Mouse; |
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