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ELK Biotechnology
SKU:ES10505
CCAR1 Rabbit Polyclonal Antibody
CCAR1 Rabbit Polyclonal Antibody
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$248.00 USD
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CCAR1 Rabbit Polyclonal Antibody
Overview
| Product name: | CCAR1 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 840-920 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 126kD |
| GeneID(Human): | 55749 |
| Human Swiss-Prot No: | Q8IX12 |
| Cellular localization: | Cytoplasm, perinuclear region . |
| Background: | function:May be involved in apoptosis signaling in the presence of the reinoid CD437. Apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. Plays a role in cell cycle progression and/or cell proliferation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Contains 1 SAP domain.,tissue specificity:Expressed in various epithelial cancer cell lines, including breast, colon, prostate, pancreatic and leukemia. Expression is regulated by growth factors., |
| Species Reactivity: | Human;Mouse |
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