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ELK Biotechnology

SKU:ES10505

CCAR1 Rabbit Polyclonal Antibody

CCAR1 Rabbit Polyclonal Antibody

Regular price $248.00 USD
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CCAR1 Rabbit Polyclonal Antibody

Overview

Product name: CCAR1 rabbit pAb
Applications: WB;ELISA
Recommended Dilutions: WB 1:500-2000 ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from human protein . at AA range: 840-920
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 126kD
GeneID(Human): 55749
Human Swiss-Prot No: Q8IX12
Cellular localization: Cytoplasm, perinuclear region .
Background: function:May be involved in apoptosis signaling in the presence of the reinoid CD437. Apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. Plays a role in cell cycle progression and/or cell proliferation.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Contains 1 SAP domain.,tissue specificity:Expressed in various epithelial cancer cell lines, including breast, colon, prostate, pancreatic and leukemia. Expression is regulated by growth factors.,
Species Reactivity: Human;Mouse
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