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ELK Biotechnology
SKU:ES10462
VPP2 Rabbit Polyclonal Antibody
VPP2 Rabbit Polyclonal Antibody
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$248.00 USD
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VPP2 Rabbit Polyclonal Antibody
Overview
| Product name: | VPP2 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from part region of human protein |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 94kD |
| GeneID(Human): | 23545 |
| Human Swiss-Prot No: | Q9Y487 |
| Cellular localization: | Cell membrane; Multi-pass membrane protein. Endosome membrane. In kidney proximal tubules, also detected in subapical vesicles. . |
| Background: | The protein encoded by this gene is a subunit of the vacuolar ATPase (v-ATPase), an heteromultimeric enzyme that is present in intracellular vesicles and in the plasma membrane of specialized cells, and which is essential for the acidification of diverse cellular components. V-ATPase is comprised of a membrane peripheral V(1) domain for ATP hydrolysis, and an integral membrane V(0) domain for proton translocation. The subunit encoded by this gene is a component of the V(0) domain. Mutations in this gene are a cause of both cutis laxa type II and wrinkly skin syndrome. [provided by RefSeq, Jul 2009], |
| Species Reactivity: | Human;Rat;Mouse; |
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