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ELK Biotechnology
SKU:ES10359
TM2D1 Rabbit Polyclonal Antibody
TM2D1 Rabbit Polyclonal Antibody
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$248.00 USD
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TM2D1 Rabbit Polyclonal Antibody
Overview
| Product name: | TM2D1 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from part region of human protein |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 22kD |
| GeneID(Human): | 83941 |
| Human Swiss-Prot No: | Q9BX74 |
| Cellular localization: | Membrane ; Multi-pass membrane protein . |
| Background: | The protein encoded by this gene is a beta-amyloid peptide-binding protein. It contains a structural module related to that of the seven transmembrane domain G protein-coupled receptor superfamily and known to be important in heterotrimeric G protein activation. Beta-amyloid peptide has been established to be a causative factor in neuron death and the consequent diminution of cognitive abilities observed in Alzheimer's disease. This protein may be a target of neurotoxic beta-amyloid peptide, and may mediate cellular vulnerability to beta-amyloid peptide toxicity through a G protein-regulated program of cell death. Several transcript variants have been found for this gene. [provided by RefSeq, Feb 2016], |
| Species Reactivity: | Human;Mouse |
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