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ELK Biotechnology

SKU:ES10343

TPSN Rabbit Polyclonal Antibody

TPSN Rabbit Polyclonal Antibody

Regular price $248.00 USD
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TPSN Rabbit Polyclonal Antibody

Overview

Product name: TPSN rabbit pAb
Applications: WB;ELISA
Recommended Dilutions: WB 1:500-2000 ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from part region of human protein
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 49kD
GeneID(Human): 6892
Human Swiss-Prot No: O15533
Cellular localization: Endoplasmic reticulum membrane ; Single-pass type I membrane protein .
Background: This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Mouse
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