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ELK Biotechnology
SKU:ES10327
SYN3 Rabbit Polyclonal Antibody
SYN3 Rabbit Polyclonal Antibody
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$248.00 USD
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SYN3 Rabbit Polyclonal Antibody
Overview
| Product name: | SYN3 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from part region of human protein. AA range 530-580 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 63kD |
| GeneID（Human）: | 8224 |
| Human Swiss-Prot No: | O14994 |
| Cellular localization: | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Peripheral membrane protein localized to the cytoplasmic surface of synaptic vesicles. |
| Background: | This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. The protein encoded by this gene shares the synapsin family domain model, with domains A, C, and E exhibiting the highest degree of conservation. The protein contains a unique domain J, located between domains C and E. Based on this gene's localization to 22q12.3, a possible schizophrenia susceptibility locus, and the established neurobiological roles of the synapsins, this family member may represent a candidate gene for schizophrenia. The TIMP3 gene is located within an intron of this gene and is transcribed in the opposite directi |
| Species Reactivity: | Human;Rat;Mouse |
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