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ELK Biotechnology

SKU:ES10262

KCNN1 Rabbit Polyclonal Antibody

KCNN1 Rabbit Polyclonal Antibody

Regular price $248.00 USD
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KCNN1 Rabbit Polyclonal Antibody

Overview

Product name: KCNN1 rabbit pAb
Applications: WB;ELISA
Recommended Dilutions: WB 1:500-2000 ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from human protein . at AA range: 360-440
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 59kD
GeneID(Human): 3780
Human Swiss-Prot No: Q92952
Cellular localization: Membrane; Multi-pass membrane protein.
Background: potassium calcium-activated channel subfamily N member 1(KCNN1) Homo sapiens Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. This gene is a member of the KCNN family of potassium channel genes. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Mouse;Rat
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