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ELK Biotechnology
SKU:ES10207
NEK1 Rabbit Polyclonal Antibody
NEK1 Rabbit Polyclonal Antibody
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$248.00 USD
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NEK1 Rabbit Polyclonal Antibody
Overview
| Product name: | NEK1 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 280-360 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 138kD |
| GeneID（Human）: | 4750 |
| Human Swiss-Prot No: | Q96PY6 |
| Cellular localization: | Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm . Associated with the pericentriolar material (PubMed:21211617). Localizes to centrosome during interphase and mitosis (By similarity). Translocated from cytoplasm to discrete nuclear foci at sites of DNA damage (PubMed:15604234). . |
| Background: | The protein encoded by this gene is a serine/threonine kinase involved in cell cycle regulation. The encoded protein is found in a centrosomal complex with FEZ1, a neuronal protein that plays a role in axonal development. Defects in this gene are a cause of polycystic kidney disease (PKD). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2010], |
| Species Reactivity: | Human;Mouse |
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