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ELK Biotechnology
SKU:ES10192
SPDEF Rabbit Polyclonal Antibody
SPDEF Rabbit Polyclonal Antibody
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$248.00 USD
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SPDEF Rabbit Polyclonal Antibody
Overview
| Product name: | SPDEF rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 140-220 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 36kD |
| GeneID(Human): | 25803 |
| Human Swiss-Prot No: | O95238 |
| Cellular localization: | Nucleus . |
| Background: | The protein encoded by this gene belongs to the ETS family of transcription factors. It is highly expressed in the prostate epithelial cells, and functions as an androgen-independent transactivator of prostate-specific antigen (PSA) promoter. Higher expression of this protein has also been reported in brain, breast, lung and ovarian tumors, compared to the corresponding normal tissues, and it shows better tumor-association than other cancer-associated molecules, making it a more suitable target for developing specific cancer therapies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011], |
| Species Reactivity: | Human;Mouse |
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