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ELK Biotechnology
SKU:ES10191
ROBO1 Rabbit Polyclonal Antibody
ROBO1 Rabbit Polyclonal Antibody
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$248.00 USD
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ROBO1 Rabbit Polyclonal Antibody
Overview
| Product name: | ROBO1 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 730-810 |
| Storage: | -20°C/1 year |
| Storage: | Rabbit |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 181kD |
| GeneID（Human）: | 6091 |
| Human Swiss-Prot No: | Q9Y6N7 |
| Cellular localization: | Cell membrane ; Single-pass type I membrane protein . Cell projection, axon . Endoplasmic reticulum-Golgi intermediate compartment membrane ; Single-pass membrane protein . Detected at growth cones in thalamus neurons. Detected at growth cones in thalamus neurons (By similarity). PRRG4 prevents cell surface location and both colocalize in the Endoplasmic reticulum/Golgi adjacent to the cell nucleus (By similarity). . |
| Background: | Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants emanating from the midline. The product of this gene is a member of the immunoglobulin gene superfamily and encodes an integral membrane protein that functions in axon guidance and neuronal precursor cell migration. This receptor is activated by SLIT-family proteins, resulting in a repulsive effect on glioma cell guidance in the developing brain. A related gene is located at an adjacent region on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009], |
| Species Reactivity: | Human;Mouse;Rat |
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