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ELK Biotechnology
SKU:ES10185
RRBP1 Rabbit Polyclonal Antibody
RRBP1 Rabbit Polyclonal Antibody
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$248.00 USD
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RRBP1 Rabbit Polyclonal Antibody
Overview
| Product name: | RRBP1 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 1120-1200 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 155kD |
| GeneID（Human）: | 6238 |
| Human Swiss-Prot No: | Q9P2E9 |
| Cellular localization: | Endoplasmic reticulum membrane ; Single-pass type III membrane protein . |
| Background: | This gene encodes a ribosome-binding protein of the endoplasmic reticulum (ER) membrane. Studies suggest that this gene plays a role in ER proliferation, secretory pathways and secretory cell differentiation, and mediation of ER-microtubule interactions. Alternative splicing has been observed and protein isoforms are characterized by regions of N-terminal decapeptide and C-terminal heptad repeats. Splicing of the tandem repeats results in variations in ribosome-binding affinity and secretory function. The full-length nature of variants which differ in repeat length has not been determined. Pseudogenes of this gene have been identified on chromosomes 3 and 7, and RRBP1 has been excluded as a candidate gene in the cause of Alagille syndrome, the result of a mutation in a nearby gene on chromosome 20p12. [provided by RefSeq, Apr 2012], |
| Species Reactivity: | Human;Mouse |
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