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ELK Biotechnology
SKU:ES10101
GRP3 Rabbit Polyclonal Antibody
GRP3 Rabbit Polyclonal Antibody
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$248.00 USD
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GRP3 Rabbit Polyclonal Antibody
Overview
| Product name: | GRP3 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 90-170 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 75kD |
| GeneID（Human）: | 25780 |
| Human Swiss-Prot No: | Q8IV61 |
| Cellular localization: | intracellular,plasma membrane,integral component of plasma membrane,guanyl-nucleotide exchange factor complex,perinuclear region of cytoplasm, |
| Background: | RAS guanyl releasing protein 3(RASGRP3) Homo sapiens Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM, Mar 2008], |
| Species Reactivity: | Human;Rat;Mouse; |
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