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ELK Biotechnology
SKU:ES10095
RPGF6 Rabbit Polyclonal Antibody
RPGF6 Rabbit Polyclonal Antibody
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$248.00 USD
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RPGF6 Rabbit Polyclonal Antibody
Overview
| Product name: | RPGF6 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 460-540 |
| Storage: | -20°C/1 year |
| Storage: | Rabbit |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 176kD |
| GeneID（Human）: | 51735 |
| Human Swiss-Prot No: | Q8TEU7 |
| Cellular localization: | Cytoplasm . Cell membrane . Upon binding to M-Ras, it translocates to the plasma membrane. |
| Background: | function:Guanine nucleotide exchange factor (GEF) for Rap1A, Rap2A and M-Ras GTPases. Does not interact with cAMP.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 cyclic nucleotide-binding domain.,similarity:Contains 1 N-terminal Ras-GEF domain.,similarity:Contains 1 PDZ (DHR) domain.,similarity:Contains 1 Ras-associating domain.,similarity:Contains 1 Ras-GEF domain.,subcellular location:Upon binding to M-Ras, it translocates to the plasma membrane.,subunit:Interacts with the second PDZ domain of human PTP1e.,tissue specificity:Isoform 3 has highest expression levels in the brain, heart, liver, lung and placenta and is barely detectable in skeletal muscle, kidney and pancreas., |
| Species Reactivity: | Human;Rat;Mouse; |
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