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ELK Biotechnology
SKU:ES10000
PI3R6 Rabbit Polyclonal Antibody
PI3R6 Rabbit Polyclonal Antibody
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$248.00 USD
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PI3R6 Rabbit Polyclonal Antibody
Overview
| Product name: | PI3R6 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 280-360 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 82kD |
| GeneID（Human）: | 146850 |
| Human Swiss-Prot No: | Q5UE93 |
| Cellular localization: | Cytoplasm . Cell membrane ; Peripheral membrane protein . Translocated to the plasma membrane in a Ras-dependent manner. . |
| Background: | Phosphoinositide 3-kinase gamma is a lipid kinase that produces the lipid second messenger phosphatidylinositol 3,4,5-trisphosphate. The kinase is composed of a catalytic subunit and one of several regulatory subunits, and is chiefly activated by G protein-coupled receptors. This gene encodes a regulatory subunit, and is distantly related to the phosphoinositide-3-kinase, regulatory subunit 5 gene which is located adjacent to this gene on chromosome 7. The orthologous protein in the mouse binds to both the catalytic subunit and to G(beta/gamma), and mediates activation of the kinase subunit downstream of G protein-coupled receptors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014], |
| Species Reactivity: | Human;Rat;Mouse; |
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