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ELK Biotechnology
SKU:ES9998
PACS1 Rabbit Polyclonal Antibody
PACS1 Rabbit Polyclonal Antibody
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$248.00 USD
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PACS1 Rabbit Polyclonal Antibody
Overview
| Product name: | PACS1 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 400-480 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 105kD |
| GeneID（Human）: | 55690 |
| Human Swiss-Prot No: | Q6VY07 |
| Cellular localization: | Golgi apparatus, trans-Golgi network . Localizes in the perinuclear region, probably the TGN. . |
| Background: | This gene encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Rat;Mouse |
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