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ELK Biotechnology
SKU:ES9989
PIGA Rabbit Polyclonal Antibody
PIGA Rabbit Polyclonal Antibody
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$248.00 USD
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PIGA Rabbit Polyclonal Antibody
Overview
| Product name: | PIGA rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 410-490 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 53kD |
| GeneID（Human）: | 5277 |
| Human Swiss-Prot No: | P37287 |
| Cellular localization: | Endoplasmic reticulum membrane; Single-pass membrane protein. |
| Background: | This gene encodes a protein required for synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the biosynthetic pathway of GPI anchor. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. Paroxysmal nocturnal hemoglobinuria, an acquired hematologic disorder, has been shown to result from mutations in this gene. Alternate splice variants have been characterized. A related pseudogene is located on chromosome 12. [provided by RefSeq, Jun 2010], |
| Species Reactivity: | Human;Mouse |
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