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ELK Biotechnology
SKU:ES9951
NOG1 Rabbit Polyclonal Antibody
NOG1 Rabbit Polyclonal Antibody
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$248.00 USD
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NOG1 Rabbit Polyclonal Antibody
Overview
| Product name: | NOG1 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 580-660 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 69kD |
| GeneID（Human）: | 23560 |
| Human Swiss-Prot No: | Q9BZE4 |
| Cellular localization: | Nucleus, nucleolus . |
| Background: | GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Rat;Mouse |
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