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ELK Biotechnology
SKU:ES9897
NRX1B Rabbit Polyclonal Antibody
NRX1B Rabbit Polyclonal Antibody
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$248.00 USD
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NRX1B Rabbit Polyclonal Antibody
Overview
| Product name: | NRX1B rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 260-340 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 48kD |
| GeneID（Human）: | 9378 |
| Human Swiss-Prot No: | P58400 |
| Cellular localization: | Cell junction, synapse, presynaptic cell membrane ; Single-pass type I membrane protein . |
| Background: | alternative products:A number of isoforms are produced by alternative promoter usage including the alpha-type (shown here) and beta-type (AC P58400) isoforms which differ in their N-terminus. Additional isoforms may be produced by alternative splicing,alternative products:A number of isoforms, alpha-type (AC Q9ULB1) and beta-type (shown here), are produced by alternative promoter usage. Beta-type isoforms differ from alpha-type isoforms in their N-terminus,function:Neuronal cell surface protein that may be involved in cell recognition and cell adhesion by forming intracellular junctions through binding to neuroligins. May play a role in formation or maintenance of synaptic junctions. May mediate intracellular signaling.,function:Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May mediate intracellular signaling.,PTM:Highly O-glycosylated and minor N-glycosylated.,PTM:N- and O-glycosylated.,similarity:Belongs to the neurexin family.,similarity:Contains 1 laminin G-like domain.,similarity:Contains 3 EGF-like domains.,similarity:Contains 6 laminin G-like domains.,subunit:The cytoplasmic C-terminal region binds to CASK, CASKIN1 and APBA1. The laminin G-like domain 2 binds to NXPH1. Specific isoforms bind to alpha-dystroglycan and to alpha-latroxin. Interacts with SYT13 and SYTL1.,subunit:The cytoplasmic C-terminal region binds to CASK. Isoforms Beta 4b bind neuroligins NLGN1, NLGN2 and NLGN3, alpha-dystroglycan and alpha-latrotoxin.,tissue specificity:Heart and brain., |
| Species Reactivity: | Human;Rat;Mouse |
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