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ELK Biotechnology
SKU:ES9887
ULA1 Rabbit Polyclonal Antibody
ULA1 Rabbit Polyclonal Antibody
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$248.00 USD
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ULA1 Rabbit Polyclonal Antibody
Overview
| Product name: | ULA1 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 390-470 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 58kD |
| GeneID（Human）: | 8883 |
| Human Swiss-Prot No: | Q13564 |
| Cellular localization: | Cell membrane . Colocalizes with APP in lipid rafts. |
| Background: | The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Rat;Mouse |
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