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ELK Biotechnology
SKU:ES9862
SIR4 Rabbit Polyclonal Antibody
SIR4 Rabbit Polyclonal Antibody
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$248.00 USD
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SIR4 Rabbit Polyclonal Antibody
Overview
| Product name: | SIR4 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 30-110 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 34kD |
| GeneID(Human): | 23409 |
| Human Swiss-Prot No: | Q9Y6E7 |
| Cellular localization: | Mitochondrion matrix . |
| Background: | This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Mouse |
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