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ELK Biotechnology
SKU:ES9769
LIPA1 Rabbit Polyclonal Antibody
LIPA1 Rabbit Polyclonal Antibody
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$248.00 USD
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LIPA1 Rabbit Polyclonal Antibody
Overview
| Product name: | LIPA1 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 980-1060 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 132kD |
| GeneID（Human）: | 8500 |
| Human Swiss-Prot No: | Q13136 |
| Cellular localization: | Cytoplasm . Colocalizes with PTPRF at the ends of focal adhesions most proximal to the cell nucleus. |
| Background: | The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions. This interaction may regulate the disassembly of focal adhesion and thus help orchestrate cell-matrix interactions. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Rat;Mouse; |
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