Synthesized peptide derived from part region of human protein
Storage:
Rabbit
Storage:
-20°C/1 year
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1 mg/ml
Observed Band:
19kD
GeneID（Human）:
6048
Human Swiss-Prot No:
Q99942
Cellular localization:
Cell membrane ; Multi-pass membrane protein . Mitochondrion membrane ; Multi-pass membrane protein . Endoplasmic reticulum membrane ; Multi-pass membrane protein . Predominantly located in the plasma membrane, with some localization occurring within cytoplasmic organelles. .
Background:
The protein encoded by this gene contains a RING finger, which is a motif known to be involved in protein-protein interactions. This protein is a membrane-bound ubiquitin ligase. It can regulate cell motility by targeting paxillin ubiquitination and altering the distribution and localization of paxillin in cytoplasm and cell focal adhesions. [provided by RefSeq, Jul 2008],
