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ELK Biotechnology
SKU:ES9598
DNA2 Rabbit Polyclonal Antibody
DNA2 Rabbit Polyclonal Antibody
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$248.00 USD
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DNA2 Rabbit Polyclonal Antibody
Overview
| Product name: | DNA2 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from part region of human protein |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 116kD |
| GeneID（Human）: | 1763 |
| Human Swiss-Prot No: | P51530 |
| Cellular localization: | Nucleus. Mitochondrion. Was initially reported to be exclusively mitochondrial (PubMed:18995831). However, it was later shown to localize both in mitochondrion and nucleus (PubMed:19487465). . |
| Background: | This gene encodes a member of the DNA2/NAM7 helicase family. The encoded protein is a conserved helicase/nuclease involved in the maintenance of mitochondrial and nuclear DNA stability. Mutations in this gene are associated with autosomal dominant progressive external ophthalmoplegia-6 (PEOA6) and Seckel syndrome 8. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014], |
| Species Reactivity: | Human;Mouse |
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